SNP Variants in Major Histocompatibility Complex Are Associated with Sarcoidosis Susceptibility—A Joint Analysis in Four European Populations

Sarcoidosis is a multiorgan inflammatory disorder with heritability estimates up to 66%. Previous studies have shown the major histocompatibility complex (MHC) region to be associated with sarcoidosis, suggesting a functional role for antigen-presenting molecules and immune mediators in the disease...

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Detalles Bibliográficos
Autores principales: Wolin, Annika, Lahtela, Elisa Laura, Anttila, Verneri, Petrek, Martin, Grunewald, Johan, van Moorsel, Coline H. M., Eklund, Anders, Grutters, Jan C., Kolek, Vitezslav, Mrazek, Frantisek, Kishore, Amit, Padyukov, Leonid, Pietinalho, Anne, Ronninger, Marcus, Seppänen, Mikko, Selroos, Olof, Lokki, Marja-Liisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395694/
https://www.ncbi.nlm.nih.gov/pubmed/28469621
http://dx.doi.org/10.3389/fimmu.2017.00422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395694/
https://www.ncbi.nlm.nih.gov/pubmed/28469621
http://dx.doi.org/10.3389/fimmu.2017.00422

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