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SNP Variants in Major Histocompatibility Complex Are Associated with Sarcoidosis Susceptibility—A Joint Analysis in Four European Populations
Sarcoidosis is a multiorgan inflammatory disorder with heritability estimates up to 66%. Previous studies have shown the major histocompatibility complex (MHC) region to be associated with sarcoidosis, suggesting a functional role for antigen-presenting molecules and immune mediators in the disease...
Autores principales: | Wolin, Annika, Lahtela, Elisa Laura, Anttila, Verneri, Petrek, Martin, Grunewald, Johan, van Moorsel, Coline H. M., Eklund, Anders, Grutters, Jan C., Kolek, Vitezslav, Mrazek, Frantisek, Kishore, Amit, Padyukov, Leonid, Pietinalho, Anne, Ronninger, Marcus, Seppänen, Mikko, Selroos, Olof, Lokki, Marja-Liisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395694/ https://www.ncbi.nlm.nih.gov/pubmed/28469621 http://dx.doi.org/10.3389/fimmu.2017.00422 |
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