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MYC selects against reduced BCL2A1/A1 protein expression during B cell lymphomagenesis

Rearrangements of MYC or ABL proto-oncogenes lead to deregulated expression of key-regulators of cell cycle and cell survival, thereby constituting important drivers of blood cancer. Members of the BCL-2 family of apoptosis regulators contribute to oncogenic transformation downstream of these oncoge...

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Detalles Bibliográficos
Autores principales: Sochalska, M, Schuler, F, Weiss, J G, Prchal-Murphy, M, Sexl, V, Villunger, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395700/
https://www.ncbi.nlm.nih.gov/pubmed/27694901
http://dx.doi.org/10.1038/onc.2016.362