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Tissue tropisms, infection kinetics, histologic lesions, and antibody response of the MR766 strain of Zika virus in a murine model

BACKGROUND: The appearance of severe Zika virus (ZIKV) disease in the most recent outbreak has prompted researchers to respond through the development of tools to quickly characterize transmission and pathology. We describe here another such tool, a mouse model of ZIKV infection and pathogenesis usi...

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Detalles Bibliográficos
Autores principales: Kawiecki, Anna B., Mayton, E. Handly, Dutuze, M. Fausta, Goupil, Brad A., Langohr, Ingeborg M., Del Piero, Fabio, Christofferson, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395720/
https://www.ncbi.nlm.nih.gov/pubmed/28420392
http://dx.doi.org/10.1186/s12985-017-0749-x