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A novel lncRNA uc.134 represses hepatocellular carcinoma progression by inhibiting CUL4A-mediated ubiquitination of LATS1

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, and tumor recurrence and metastasis are major factors that contribute to the poor outcome of patients with HCC. Long noncoding RNAs (lncRNAs) are known to regulate different tumorigenic processes, and a grow...

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Detalles Bibliográficos
Autores principales: Ni, Wen, Zhang, Yuqin, Zhan, Zetao, Ye, Feng, Liang, Yonghao, Huang, Jing, Chen, Keli, Chen, Longhua, Ding, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395742/
https://www.ncbi.nlm.nih.gov/pubmed/28420424
http://dx.doi.org/10.1186/s13045-017-0449-4