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Autophagy mediates the beneficial effect of hypoxic preconditioning on bone marrow mesenchymal stem cells for the therapy of myocardial infarction

BACKGROUND: Stem cell therapy has emerged as a promising therapeutic strategy for myocardial infarction (MI). However, the poor viability of transplanted stem cells hampers their therapeutic efficacy. Hypoxic preconditioning (HPC) can effectively promote the survival of stem cells. The aim of this s...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng, Yang, Chao, Shen, Mingzhi, Yang, Ming, Jin, Zhitao, Ding, Liping, Jiang, Wei, Yang, Junke, Chen, Haixu, Cao, Feng, Hu, Taohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395756/
https://www.ncbi.nlm.nih.gov/pubmed/28420436
http://dx.doi.org/10.1186/s13287-017-0543-0