Elevated Gab2 induces tumor growth and angiogenesis in colorectal cancer through upregulating VEGF levels

BACKGROUND: Grb2-associated binder 2 (Gab2) is a scaffolding protein that serves as a critical signaling amplifier downstream of tyrosine kinase receptors. Our previous study has shown that Gab2 induces epithelial-to-mesenchymal transition (EMT) and promotes metastasis in colorectal cancer (CRC). Ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Chenbo, Luo, Junmin, Fan, Xiaobo, Li, Longmei, Li, Shanshan, Wen, Kunming, Feng, Jihong, Wu, Guoqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395829/
https://www.ncbi.nlm.nih.gov/pubmed/28420432
http://dx.doi.org/10.1186/s13046-017-0524-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395829/
https://www.ncbi.nlm.nih.gov/pubmed/28420432
http://dx.doi.org/10.1186/s13046-017-0524-2

Ejemplares similares