Cargando…

Tau phosphorylation induced by severe closed head traumatic brain injury is linked to the cellular prion protein

Studies in vivo and in vitro have suggested that the mechanism underlying Alzheimer’s disease (AD) neuropathogenesis is initiated by an interaction between the cellular prion protein (PrP(C)) and amyloid-β oligomers (Aβo). This PrP(C)-Aβo complex activates Fyn kinase which, in turn, hyperphosphoryla...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rubenstein, Richard, Chang, Binggong, Grinkina, Natalia, Drummond, Eleanor, Davies, Peter, Ruditzky, Meir, Sharma, Deep, Wang, Kevin, Wisniewski, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395835/ https://www.ncbi.nlm.nih.gov/pubmed/28420443 http://dx.doi.org/10.1186/s40478-017-0435-7

Ejemplares similares

T-Tau and P-Tau in Brain and Blood from Natural and Experimental Prion Diseases
por: Rubenstein, Richard, et al.
Publicado: (2015)

Novel Mouse Tauopathy Model for Repetitive Mild Traumatic Brain Injury: Evaluation of Long-Term Effects on Cognition and Biomarker Levels After Therapeutic Inhibition of Tau Phosphorylation
por: Rubenstein, Richard, et al.
Publicado: (2019)

Influence of Mabs on PrP(Sc) Formation Using In Vitro and Cell-Free Systems
por: Chang, Binggong, et al.
Publicado: (2012)

Righting Reflex Predicts Long-Term Histological and Behavioral Outcomes in a Closed Head Model of Traumatic Brain Injury
por: Grin’kina, Natalia M., et al.
Publicado: (2016)

Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer’s disease and not in other tauopathies
por: Pires, Geoffrey, et al.
Publicado: (2019)

It takes more than tau to tangle: using proteomics to determine how phosphorylated tau mediates toxicity in neurodegenerative diseases
por: Pires, Geoffrey, et al.
Publicado: (2021)

Targeting Prion-like Cis Phosphorylated Tau Pathology in Neurodegenerative Diseases
por: Albayram, Onder, et al.
Publicado: (2018)

Tau Protein Phosphorylated at Threonine-231 is Expressed Abundantly in the Cerebellum in Prion Encephalopathies
por: Gómez-López, Vıctor Manuel, et al.
Publicado: (2021)

Re-Assessment of PrP(Sc) Distribution in Sporadic and Variant CJD
por: Rubenstein, Richard, et al.
Publicado: (2013)

Phosphorylation of nuclear Tau is modulated by distinct cellular pathways
por: Ulrich, Giorgio, et al.
Publicado: (2018)

Cellular Prion Protein Is Closely Associated with Early Recurrence and Poor Survival in Patients with Hepatocellular Carcinoma
por: Kim, Mo-Jong, et al.
Publicado: (2022)

Outcome of Decompressive Craniectomy in Traumatic Closed Head Injury
por: Laghari, Altaf Ali, et al.
Publicado: (2018)

Tau, prions and Aβ: the triad of neurodegeneration
por: Reiniger, Lilla, et al.
Publicado: (2010)

Structure of Tau filaments in Prion protein amyloidoses
por: Hallinan, Grace I., et al.
Publicado: (2021)

The Prion 2018 round tables (II): Aβ, tau, α-synuclein… are they prions, prion-like proteins, or what?
por: Eraña, Hasier
Publicado: (2019)

Endoproteolysis of cellular prion protein by plasmin hinders propagation of prions
por: Mays, Charles E., et al.
Publicado: (2022)

Prion propagation and cellular dysfunction in prion disease: Disconnecting the dots
por: Foliaki, Simote T., et al.
Publicado: (2023)

The Cellular Distribution and Ser262 Phosphorylation of Tau Protein Are Regulated by BDNF In Vitro
por: Chen, Qian, et al.
Publicado: (2014)

No full admission for tau to the exclusive prion club yet
por: Polanco, Juan Carlos, et al.
Publicado: (2015)

The prion-like transmission of tau oligomers via exosomes
por: Jackson, Noel A., et al.
Publicado: (2022)

AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo
por: Domise, Manon, et al.
Publicado: (2016)

Tau Lysine Pseudomethylation Regulates Microtubule Binding and Enhances Prion-like Tau Aggregation
por: Xia, Yuxing, et al.
Publicado: (2023)

Neurotoxicity of Prion Peptides Mimicking the Central Domain of the Cellular Prion Protein
por: Vilches, Silvia, et al.
Publicado: (2013)

Tau interactome and RNA binding proteins in neurodegenerative diseases
por: Kavanagh, Tomas, et al.
Publicado: (2022)

Aβ seeds and prions: How close the fit?
por: Rasmussen, Jay, et al.
Publicado: (2017)

Haloperidol inactivates AMPK and reduces tau phosphorylation in a tau mouse model of Alzheimer's disease
por: Koppel, Jeremy, et al.
Publicado: (2016)

Amyloid- and tau-PET imaging in a familial prion kindred
por: Jones, David T., et al.
Publicado: (2018)

Aβ and tau prions feature in the neuropathogenesis of Down syndrome
por: Condello, Carlo, et al.
Publicado: (2022)

Cellular Aspects of Prion Replication In Vitro
por: Grassmann, Andrea, et al.
Publicado: (2013)

α-Cleavage of cellular prion protein
por: Liang, Jingjing, et al.
Publicado: (2012)

Physiological Functions of the Cellular Prion Protein
por: Castle, Andrew R., et al.
Publicado: (2017)

The Cellular Prion Protein and the Hallmarks of Cancer
por: Mouillet-Richard, Sophie, et al.
Publicado: (2021)

Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature
por: Kahriman, Aydan, et al.
Publicado: (2021)

The Evolution of Tau Phosphorylation and Interactions
por: Trushina, Nataliya I., et al.
Publicado: (2019)

Anti-β-sheet conformation monoclonal antibody reduces tau and Aβ oligomer pathology in an Alzheimer’s disease model
por: Goñi, Fernando, et al.
Publicado: (2018)

Guam ALS-PDC is a distinct double-prion disorder featuring both tau and Aβ prions
por: Condello, Carlo, et al.
Publicado: (2023)

The use of localized proteomics to identify the drivers of Alzheimer's disease pathogenesis
por: Drummond, Eleanor, et al.
Publicado: (2017)

APOE-amyloid interaction: Therapeutic targets
por: Wisniewski, Thomas, et al.
Publicado: (2020)

The Expression of Cellular Prion Protein, PrPC, Favors pTau Propagation and Blocks NMDAR Signaling in Primary Cortical Neurons
por: Rivas-Santisteban, Rafael, et al.
Publicado: (2023)

Abeta is prerequisite, but insufficient to cause tau phosphorylation in vivo: tau phosphorylation in APP mice by diabetes
por: Sato, Naoyuki
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_c9d768n3ovvbsqp677ldhk0g5b