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The risk of bias in randomized controlled trials in otorhinolaryngology: hardly any improvement since 1950
BACKGROUND: Randomized Controlled Trials (RCTs) represent the most valuable study design to evaluate the effectiveness of therapeutic interventions. However, flaws in design, conduct, analysis, and reporting of RCTs can cause the effect of an intervention to be under- or overestimated. These biased...
Autores principales: | Peters, Jeroen P. M., Stegeman, Inge, Grolman, Wilko, Hooft, Lotty |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395869/ https://www.ncbi.nlm.nih.gov/pubmed/28428729 http://dx.doi.org/10.1186/s12901-017-0036-x |
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