Genome-wide search for candidate genes for yeast robustness improvement against formic acid reveals novel susceptibility (Trk1 and positive regulators) and resistance (Haa1-regulon) determinants

BACKGROUND: Formic acid is an inhibitory compound present in lignocellulosic hydrolysates. Understanding the complex molecular mechanisms underlying Saccharomyces cerevisiae tolerance to this weak acid at the system level is instrumental to guide synthetic pathway engineering for robustness improvem...

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Detalles Bibliográficos
Autores principales: Henriques, Sílvia F., Mira, Nuno P., Sá-Correia, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395885/
https://www.ncbi.nlm.nih.gov/pubmed/28428821
http://dx.doi.org/10.1186/s13068-017-0781-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395885/
https://www.ncbi.nlm.nih.gov/pubmed/28428821
http://dx.doi.org/10.1186/s13068-017-0781-5

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