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Umbilical cord-derived mesenchymal stem cells on scaffolds facilitate collagen degradation via upregulation of MMP-9 in rat uterine scars

BACKGROUND: Severe injuries of the uterus may trigger uterine scar formation, ultimately leading to infertility or obstetrical complications. To date, few methods have adequately solved the problem of collagen deposition in uterine scars. Umbilical cord-derived mesenchymal stem cells (UC-MSCs) have...

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Detalles Bibliográficos
Autores principales: Xu, Lu, Ding, Lijun, Wang, Lei, Cao, Yun, Zhu, Hui, Lu, Jingjie, Li, Xin’an, Song, Tianran, Hu, Yali, Dai, Jianwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395893/
https://www.ncbi.nlm.nih.gov/pubmed/28420433
http://dx.doi.org/10.1186/s13287-017-0535-0