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Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine

The leading malaria vaccine in development is the circumsporozoite protein (CSP)-based particle vaccine, RTS,S, which targets the pre-erythrocytic stage of Plasmodium falciparum infection. It induces modest levels of protective efficacy, thought to be mediated primarily by CSP-specific antibodies. W...

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Detalles Bibliográficos
Autores principales: Collins, Katharine A., Snaith, Rebecca, Cottingham, Matthew G., Gilbert, Sarah C., Hill, Adrian V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395940/
https://www.ncbi.nlm.nih.gov/pubmed/28422178
http://dx.doi.org/10.1038/srep46621