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G protein-coupled KISS1 receptor is overexpressed in triple negative breast cancer and promotes drug resistance

Triple-negative breast cancer (TNBC) lacks the expression of estrogen receptor α, progesterone receptor and human epidermal growth factor receptor 2 (HER2). TNBC patients lack targeted therapies, as they fail to respond to endocrine and anti-HER2 therapy. Prognosis for this aggressive cancer subtype...

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Detalles Bibliográficos
Autores principales: Blake, Alexandra, Dragan, Magdalena, Tirona, Rommel G., Hardy, Daniel B., Brackstone, Muriel, Tuck, Alan B., Babwah, Andy V., Bhattacharya, Moshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395950/
https://www.ncbi.nlm.nih.gov/pubmed/28422142
http://dx.doi.org/10.1038/srep46525