Spastic paraplegia-linked phospholipase PAPLA1 is necessary for development, reproduction, and energy metabolism in Drosophila

The human PAPLA1 phospholipase family is associated with hereditary spastic paraplegia (HSP), a neurodegenerative syndrome characterized by progressive spasticity and weakness of the lower limbs. Taking advantage of a new Drosophila PAPLA1 mutant, we describe here novel functions of this phospholipa...

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Detalles Bibliográficos
Autores principales: Gáliková, Martina, Klepsatel, Peter, Münch, Judith, Kühnlein, Ronald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395975/
https://www.ncbi.nlm.nih.gov/pubmed/28422159
http://dx.doi.org/10.1038/srep46516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395975/
https://www.ncbi.nlm.nih.gov/pubmed/28422159
http://dx.doi.org/10.1038/srep46516

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