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Spastic paraplegia-linked phospholipase PAPLA1 is necessary for development, reproduction, and energy metabolism in Drosophila

The human PAPLA1 phospholipase family is associated with hereditary spastic paraplegia (HSP), a neurodegenerative syndrome characterized by progressive spasticity and weakness of the lower limbs. Taking advantage of a new Drosophila PAPLA1 mutant, we describe here novel functions of this phospholipa...

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Detalles Bibliográficos
Autores principales:	Gáliková, Martina, Klepsatel, Peter, Münch, Judith, Kühnlein, Ronald P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395975/ https://www.ncbi.nlm.nih.gov/pubmed/28422159 http://dx.doi.org/10.1038/srep46516

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