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Dynamic changes in DNA demethylation in the tree shrew (Tupaia belangeri chinensis) brain during postnatal development and aging

Brain development and aging are associated with alterations in multiple epigenetic systems, including DNA methylation and demethylation patterns. Here, we observed that the levels of the 5-hydroxymethylcytosine (5hmC) ten-eleven translocation (TET) enzyme-mediated active DNA demethylation products w...

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Detalles Bibliográficos
Autores principales: Wei, Shu, Hua, Hai-Rong, Chen, Qian-Quan, Zhang, Ying, Chen, Fei, Li, Shu-Qing, Li, Fan, Li, Jia-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396032/
https://www.ncbi.nlm.nih.gov/pubmed/28409505
http://dx.doi.org/10.24272/j.issn.2095-8137.2017.013