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Distorted Immunodominance by Linker Sequences or other Epitopes from a Second Protein Antigen During Antigen-Processing

The immune system focuses on and responds to very few representative immunodominant epitopes from pathogenic insults. However, due to the complexity of the antigen processing, understanding the parameters that lead to immunodominance has proved difficult. In an attempt to uncover the determinants of...

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Detalles Bibliográficos
Autores principales: Kim, AeRyon, Boronina, Tatiana N., Cole, Robert N., Darrah, Erika, Sadegh-Nasseri, Scheherazade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396073/
https://www.ncbi.nlm.nih.gov/pubmed/28422163
http://dx.doi.org/10.1038/srep46418