Exome Analysis of Rare and Common Variants within the NOD Signaling Pathway

Pediatric inflammatory bowel disease (pIBD) is a chronic heterogeneous disorder. This study looks at the burden of common and rare coding mutations within 41 genes comprising the NOD signaling pathway in pIBD patients. 136 pIBD and 106 control samples underwent whole-exome sequencing. We compared th...

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Detalles Bibliográficos
Autores principales: Andreoletti, Gaia, Shakhnovich, Valentina, Christenson, Kathy, Coelho, Tracy, Haggarty, Rachel, Afzal, Nadeem A, Batra, Akshay, Petersen, Britt-Sabina, Mort, Matthew, Beattie, R. Mark, Ennis, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396125/
https://www.ncbi.nlm.nih.gov/pubmed/28422189
http://dx.doi.org/10.1038/srep46454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396125/
https://www.ncbi.nlm.nih.gov/pubmed/28422189
http://dx.doi.org/10.1038/srep46454

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