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Applying causal mediation methods to clinical trial data: What can we learn about why our interventions (don't) work?

BACKGROUND: Many randomized controlled trials (RCTs) of psychosocial interventions for low back pain (LBP) have been found to have only small effects on disability outcomes. Investigations of the specific mechanisms that may lead to an improvement in outcome have therefore been called for. METHODS:...

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Detalles Bibliográficos
Autores principales: Whittle, R., Mansell, G., Jellema, P., van der Windt, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396132/
https://www.ncbi.nlm.nih.gov/pubmed/27739626
http://dx.doi.org/10.1002/ejp.964