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Simultaneous generation of multi‐gene knockouts in human cells
Genome‐editing techniques enable the generation of gene knockouts in various mammalian cell lines. However, it remains technically challenging to completely disrupt a targeted gene using a canonical method in a timely manner. To improve the efficiency of producing reliable genomic modifications, we...
Autores principales: | Zhou, Yuexin, Zhang, Hongmin, Wei, Wensheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396285/ https://www.ncbi.nlm.nih.gov/pubmed/27800615 http://dx.doi.org/10.1002/1873-3468.12469 |
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