Ammonia mediates cortical hemichannel dysfunction in rodent models of chronic liver disease

The pathogenesis of hepatic encephalopathy (HE) in cirrhosis is multifactorial and ammonia is thought to play a key role. Astroglial dysfunction is known to be present in HE. Astrocytes are extensively connected by gap junctions formed of connexins, which also exist as functional hemichannels allowi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hadjihambi, Anna, De Chiara, Francesco, Hosford, Patrick S., Habtetion, Abeba, Karagiannis, Anastassios, Davies, Nathan, Gourine, Alexander V., Jalan, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Liver Failure/Cirrhosis/Portal Hypertension
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396295/
https://www.ncbi.nlm.nih.gov/pubmed/28066916
http://dx.doi.org/10.1002/hep.29031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396295/
https://www.ncbi.nlm.nih.gov/pubmed/28066916
http://dx.doi.org/10.1002/hep.29031

Ejemplares similares