The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice

Group II metabotropic glutamate receptor agonists have been suggested as potential anti‐psychotics, at least in part, based on the observation that the agonist LY354740 appeared to rescue the cognitive deficits caused by non‐competitive N‐methyl‐d‐aspartate receptor (NMDAR) antagonists, including sp...

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Detalles Bibliográficos
Autores principales: Boerner, Thomas, Bygrave, Alexei M., Chen, Jingkai, Fernando, Anushka, Jackson, Stephanie, Barkus, Chris, Sprengel, Rolf, Seeburg, Peter H., Harrison, Paul J., Gilmour, Gary, Bannerman, David M., Sanderson, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Behavioural Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396315/
https://www.ncbi.nlm.nih.gov/pubmed/28186680
http://dx.doi.org/10.1111/ejn.13539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396315/
https://www.ncbi.nlm.nih.gov/pubmed/28186680
http://dx.doi.org/10.1111/ejn.13539

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