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Determination of differentially regulated proteins upon proteasome inhibition in AML cell lines by the combination of large‐scale and targeted quantitative proteomics

The ubiquitin‐proteasome pathway (UPP) plays a critical role in the degradation of proteins implicated in cell cycle control, signal transduction, DNA damage response, apoptosis and immune response. Proteasome inhibitors can inhibit the growth of a broad spectrum of human cancer cells by altering th...

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Detalles Bibliográficos
Autores principales: Matondo, Mariette, Marcellin, Marlène, Chaoui, Karima, Bousquet‐Dubouch, Marie‐Pierre, Gonzalez‐de‐Peredo, Anne, Monsarrat, Bernard, Burlet‐Schiltz, Odile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396343/
https://www.ncbi.nlm.nih.gov/pubmed/27709814
http://dx.doi.org/10.1002/pmic.201600089