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Quaking Is a Key Regulator of Endothelial Cell Differentiation, Neovascularization, and Angiogenesis

The capability to derive endothelial cell (ECs) from induced pluripotent stem cells (iPSCs) holds huge therapeutic potential for cardiovascular disease. This study elucidates the precise role of the RNA‐binding protein Quaking isoform 5 (QKI‐5) during EC differentiation from both mouse and human iPS...

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Detalles Bibliográficos
Autores principales: Cochrane, Amy, Kelaini, Sophia, Tsifaki, Marianna, Bojdo, James, Vilà‐González, Marta, Drehmer, Daiana, Caines, Rachel, Magee, Corey, Eleftheriadou, Magdalini, Hu, Yanhua, Grieve, David, Stitt, Alan W., Zeng, Lingfang, Xu, Qingbo, Margariti, Andriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396345/
https://www.ncbi.nlm.nih.gov/pubmed/28207177
http://dx.doi.org/10.1002/stem.2594