A Single Zidovudine (AZT) Administration Delays Hepatic Cell Proliferation by Altering Oxidative State in the Regenerating Rat Liver

The 3′-azido-3′-deoxythymidine or Zidovudine (AZT) was the first antiretroviral drug used in the treatment of HIV patients, which has good effectiveness but also hepatotoxic side effects that include cell cycle arrest and oxidative/nitrative mitochondrial damage. Whether such an oxidative damage may...

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Detalles Bibliográficos
Autores principales: Butanda-Ochoa, Armando, Hernández-Espinosa, Diego Rolando, Olguín-Martínez, Marisela, Sánchez-Sevilla, Lourdes, Rodríguez, Mario R., Chávez-Rentería, Benito, Aranda-Fraustro, Alberto, Hernández-Muñoz, Rolando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396445/
https://www.ncbi.nlm.nih.gov/pubmed/28479956
http://dx.doi.org/10.1155/2017/8356175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396445/
https://www.ncbi.nlm.nih.gov/pubmed/28479956
http://dx.doi.org/10.1155/2017/8356175

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