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Cross-reactive dengue human monoclonal antibody prevents severe pathologies and death from Zika virus infections

Zika virus (ZIKV) infections have been linked with neurological complications and congenital Zika syndrome. Given the high level of homology between ZIKV and the related flavivirus dengue virus (DENV), we investigated the level of cross-reactivity with ZIKV using a panel of DENV human mAbs. A majori...

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Detalles Bibliográficos
Autores principales: Kam, Yiu-Wing, Lee, Cheryl Yi-Pin, Teo, Teck-Hui, Howland, Shanshan W., Amrun, Siti Naqiah, Lum, Fok-Moon, See, Peter, Kng, Nicholas Qing-Rong, Huber, Roland G., Xu, Mei-Hui, Tan, Heng-Liang, Choo, Andre, Maurer-Stroh, Sebastian, Ginhoux, Florent, Fink, Katja, Wang, Cheng-I, Ng, Lisa F.P., Rénia, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396524/
https://www.ncbi.nlm.nih.gov/pubmed/28422757
http://dx.doi.org/10.1172/jci.insight.92428