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Cross-reactive dengue human monoclonal antibody prevents severe pathologies and death from Zika virus infections
Zika virus (ZIKV) infections have been linked with neurological complications and congenital Zika syndrome. Given the high level of homology between ZIKV and the related flavivirus dengue virus (DENV), we investigated the level of cross-reactivity with ZIKV using a panel of DENV human mAbs. A majori...
Autores principales: | Kam, Yiu-Wing, Lee, Cheryl Yi-Pin, Teo, Teck-Hui, Howland, Shanshan W., Amrun, Siti Naqiah, Lum, Fok-Moon, See, Peter, Kng, Nicholas Qing-Rong, Huber, Roland G., Xu, Mei-Hui, Tan, Heng-Liang, Choo, Andre, Maurer-Stroh, Sebastian, Ginhoux, Florent, Fink, Katja, Wang, Cheng-I, Ng, Lisa F.P., Rénia, Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396524/ https://www.ncbi.nlm.nih.gov/pubmed/28422757 http://dx.doi.org/10.1172/jci.insight.92428 |
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