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Estrogenic and cytotoxic potentials of compounds isolated from Millettia macrophylla Benth (Fabaceae): towards a better understanding of its underlying mechanisms

BACKGROUND: Millettia macrophylla was previously reported to have estrogenic effects and to prevent postmenopausal osteoporosis in Wistar rats. So, the study deals with the identification of its secondary metabolites and the evaluation of their estrogenicity and cytotoxicity toward tumoural cells. T...

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Detalles Bibliográficos
Autores principales: Zingue, Stéphane, Tchoumtchoua, Job, Ntsa, Dieudonnée Mireille, Sandjo, Louis Pergaud, Cisilotto, Julia, Nde, Chantal Beatrice Magne, Winter, Evelyn, Awounfack, Charline Florence, Ndinteh, Derek Tantoh, Clyne, Colin, Njamen, Dieudonné, Halabalaki, Maria, Creczynski-Pasa, Tânia Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396542/
https://www.ncbi.nlm.nih.gov/pubmed/27784319
http://dx.doi.org/10.1186/s12906-016-1385-5