Chronic activation of PPARα with fenofibrate reduces autophagic proteins in the liver of mice independent of FGF21

Autophagy is a catabolic mechanism to degrade cellular components to maintain cellular energy levels during starvation, a condition where PPARα may be activated. Here we report a reduced autophagic capacity in the liver following chronic activation of PPARα with fenofibrate (FB) in mice. Chronic adm...

Descripción completa

Detalles Bibliográficos
Autores principales: Jo, Eunjung, Li, Songpei, Liang, Qingning, Zhang, Xinmei, Wang, Hao, Herbert, Terence P., Jenkins, Trisha A., Xu, Aimin, Ye, Ji-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396863/
https://www.ncbi.nlm.nih.gov/pubmed/28422956
http://dx.doi.org/10.1371/journal.pone.0173676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396863/
https://www.ncbi.nlm.nih.gov/pubmed/28422956
http://dx.doi.org/10.1371/journal.pone.0173676

Ejemplares similares