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Th17 micro-milieu regulates NLRP1-dependent caspase-5 activity in skin autoinflammation

IL-1β is a potent player in cutaneous inflammation and central for the development of a Th17 micro-milieu in autoinflammatory diseases including psoriasis. Its production is controlled at the transcriptional level and by subsequent posttranslational processing via inflammatory caspases. In this stud...

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Detalles Bibliográficos
Autores principales: Zwicker, Stephanie, Hattinger, Eva, Bureik, Daniela, Batycka-Baran, Aleksandra, Schmidt, Andreas, Gerber, Peter-Arne, Rothenfusser, Simon, Gilliet, Michel, Ruzicka, Thomas, Wolf, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396864/
https://www.ncbi.nlm.nih.gov/pubmed/28422993
http://dx.doi.org/10.1371/journal.pone.0175153