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Inhibition of PCSK9 protects against radiation-induced damage of prostate cancer cells

BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protein expressed primarily in the liver, formerly known to maintain plasma lipid homeostasis by regulating low-density lipoprotein receptor levels, and its exact role in the radioresistance of prostate cancer (PCa) remains uncle...

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Detalles Bibliográficos
Autores principales: Gan, Si-Shun, Ye, Jian-Qing, Wang, Lei, Qu, Fa-Jun, Chu, Chuan-Min, Tian, Yi-Jun, Yang, Wei, Cui, Xin-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396925/
https://www.ncbi.nlm.nih.gov/pubmed/28442922
http://dx.doi.org/10.2147/OTT.S129413