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Magnetic and pH dual-responsive mesoporous silica nanocomposites for effective and low-toxic photodynamic therapy

Nonspecific targeting, large doses and phototoxicity severely hamper the clinical effect of photodynamic therapy (PDT). In this work, superparamagnetic Fe(3)O(4) mesoporous silica nanoparticles grafted by pH-responsive block polymer polyethylene glycol-b-poly(aspartic acid) (PEG-b-PAsp) were fabrica...

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Detalles Bibliográficos
Autores principales: Zhan, Jieqiong, Ma, Zhiqiang, Wang, Dan, Li, Xinfang, Li, Xiangui, Le, Lijing, Kang, Anfeng, Hu, Pengwei, She, Lan, Yang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396969/
https://www.ncbi.nlm.nih.gov/pubmed/28442903
http://dx.doi.org/10.2147/IJN.S127528