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The efficacy and safety of S-flurbiprofen plaster in the treatment of knee osteoarthritis: a phase II, randomized, double-blind, placebo-controlled, dose-finding study

BACKGROUND: Nonsteroidal anti-inflammatory drug (NSAID) patches are convenient for use and show much less gastrointestinal side effects than oral NSAIDs, whereas its percutaneous absorption is not sufficient for the expression of clinical efficacy at satisfactory level. S-flurbiprofen plaster (SFPP)...

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Detalles Bibliográficos
Autores principales: Yataba, Ikuko, Otsuka, Noboru, Matsushita, Isao, Matsumoto, Hideo, Hoshino, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396977/
https://www.ncbi.nlm.nih.gov/pubmed/28442928
http://dx.doi.org/10.2147/JPR.S131779