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The efficacy and safety of S-flurbiprofen plaster in the treatment of knee osteoarthritis: a phase II, randomized, double-blind, placebo-controlled, dose-finding study
BACKGROUND: Nonsteroidal anti-inflammatory drug (NSAID) patches are convenient for use and show much less gastrointestinal side effects than oral NSAIDs, whereas its percutaneous absorption is not sufficient for the expression of clinical efficacy at satisfactory level. S-flurbiprofen plaster (SFPP)...
Autores principales: | Yataba, Ikuko, Otsuka, Noboru, Matsushita, Isao, Matsumoto, Hideo, Hoshino, Yuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396977/ https://www.ncbi.nlm.nih.gov/pubmed/28442928 http://dx.doi.org/10.2147/JPR.S131779 |
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