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Challenges in enumeration of CTCs in breast cancer using techniques independent of cytokeratin expression

INTRODUCTION: Given the current postulated plasticity between epithelial and mesenchymal states of migratory cancer cells the detection of non-epithelial CTCs is an important scientific and clinical goal. METHODS: We used the filtration-based ISET technology to enrich circulating tumour cells (CTCs)...

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Detalles Bibliográficos
Autores principales: Castle, John, Morris, Karen, Pritchard, Susan, Kirwan, Cliona C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397021/
https://www.ncbi.nlm.nih.gov/pubmed/28422972
http://dx.doi.org/10.1371/journal.pone.0175647