Genetic and epigenetic changes in host ABCB1 influences malaria susceptibility to Plasmodium falciparum

Multiple mechanisms such as genetic and epigenetic variations within a key gene may play a role in malarial susceptibility and response to anti-malarial drugs in the population. ABCB1 is one of the well-studied membrane transporter genes that code for the P-glycoprotein (an efflux protein) and whose...

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Detalles Bibliográficos
Autores principales: Gupta, Himanshu, Chaudhari, Sima, Rai, Ayushi, Bhat, Smitha, Sahu, Pratima K, Hande, Manjunath H., D’Souza, Sydney C., Shashikiran, Umakanth, Satyamoorthy, Kapaettu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397027/
https://www.ncbi.nlm.nih.gov/pubmed/28422980
http://dx.doi.org/10.1371/journal.pone.0175702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397027/
https://www.ncbi.nlm.nih.gov/pubmed/28422980
http://dx.doi.org/10.1371/journal.pone.0175702

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