Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells

Nuclear lamins support the nuclear envelope and provide anchorage sites for chromatin. They are involved in DNA synthesis, transcription, and replication. It has previously been reported that the lack of Lamin A/C expression in lymphoma and leukaemia is due to CpG island promoter hypermethylation. H...

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Detalles Bibliográficos
Autores principales: Rauschert, Ines, Aldunate, Fabian, Preussner, Jens, Arocena-Sutz, Miguel, Peraza, Vanina, Looso, Mario, Benech, Juan C., Agrelo, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397038/
https://www.ncbi.nlm.nih.gov/pubmed/28422997
http://dx.doi.org/10.1371/journal.pone.0175953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397038/
https://www.ncbi.nlm.nih.gov/pubmed/28422997
http://dx.doi.org/10.1371/journal.pone.0175953

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