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Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells
Nuclear lamins support the nuclear envelope and provide anchorage sites for chromatin. They are involved in DNA synthesis, transcription, and replication. It has previously been reported that the lack of Lamin A/C expression in lymphoma and leukaemia is due to CpG island promoter hypermethylation. H...
Autores principales: | Rauschert, Ines, Aldunate, Fabian, Preussner, Jens, Arocena-Sutz, Miguel, Peraza, Vanina, Looso, Mario, Benech, Juan C., Agrelo, Ruben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397038/ https://www.ncbi.nlm.nih.gov/pubmed/28422997 http://dx.doi.org/10.1371/journal.pone.0175953 |
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