Transforming growth factor β1 enhances heme oxygenase 1 expression in human synovial fibroblasts by inhibiting microRNA 519b synthesis

BACKGROUND: Osteoarthritis (OA) is manifested by synovial inflammation and cartilage destruction that is directly linked to synovitis, joint swelling and pain. In the light of the role of synovium in the pathogenesis and the symptoms of OA, synovium-targeted therapy is a promising strategy to mitiga...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuo, Shu-Jui, Yang, Wei-Hung, Liu, Shan-Chi, Tsai, Chun-Hao, Hsu, Horng-Chaung, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397058/
https://www.ncbi.nlm.nih.gov/pubmed/28423042
http://dx.doi.org/10.1371/journal.pone.0176052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397058/
https://www.ncbi.nlm.nih.gov/pubmed/28423042
http://dx.doi.org/10.1371/journal.pone.0176052

Ejemplares similares