15-hydroxyprostaglandin dehydrogenase (15-PGDH) prevents lipopolysaccharide (LPS)-induced acute liver injury

The NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) catalyzes the oxidation of the 15(S)-hydroxyl group of prostaglandin E(2) (PGE(2)), converting the pro-inflammatory PGE(2) to the anti-inflammatory 15-keto-PGE(2) (an endogenous ligand for peroxisome proliferator-activated receptor-g...

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Detalles Bibliográficos
Autores principales: Yao, Lu, Chen, Weina, Song, Kyoungsub, Han, Chang, Gandhi, Chandrashekhar R., Lim, Kyu, Wu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397067/
https://www.ncbi.nlm.nih.gov/pubmed/28423012
http://dx.doi.org/10.1371/journal.pone.0176106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397067/
https://www.ncbi.nlm.nih.gov/pubmed/28423012
http://dx.doi.org/10.1371/journal.pone.0176106

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