Cargando…

15-hydroxyprostaglandin dehydrogenase (15-PGDH) prevents lipopolysaccharide (LPS)-induced acute liver injury

The NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) catalyzes the oxidation of the 15(S)-hydroxyl group of prostaglandin E(2) (PGE(2)), converting the pro-inflammatory PGE(2) to the anti-inflammatory 15-keto-PGE(2) (an endogenous ligand for peroxisome proliferator-activated receptor-g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Lu, Chen, Weina, Song, Kyoungsub, Han, Chang, Gandhi, Chandrashekhar R., Lim, Kyu, Wu, Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397067/ https://www.ncbi.nlm.nih.gov/pubmed/28423012 http://dx.doi.org/10.1371/journal.pone.0176106

Ejemplares similares

15-Hydroxyprostaglandin dehydrogenase inhibitor prevents contrast-induced acute kidney injury
por: Kim, Byeong Woo, et al.
Publicado: (2021)

Decreased Expression of 15-hydroxyprostaglandin Dehydrogenase in Gastric Carcinomas
por: Jang, Tae Jung, et al.
Publicado: (2008)

Relationship between 15-hydroxyprostaglandin dehydrogenase and gastric adenocarcinoma
por: Kang, Jae Hyun, et al.
Publicado: (2014)

15-Hydroxyprostaglandin Dehydrogenase Is a Predictor of Stroke-Associated Pneumonia
por: Xu, Yunfei, et al.
Publicado: (2022)

Downregulation of 15-hydroxyprostaglandin dehydrogenase in hormone-resistant breast cancer
por: Cummings, M, et al.
Publicado: (2008)

Genetic Variation in 15-Hydroxyprostaglandin Dehydrogenase and Colon Cancer Susceptibility
por: Thompson, Cheryl L., et al.
Publicado: (2013)

Role of 15-hydroxyprostaglandin dehydrogenase down-regulation on the prognosis of hepatocellular carcinoma
por: Yang, Jee Eun, et al.
Publicado: (2014)

Prognostic Implication of 15-Hydroxyprostaglandin Dehydrogenase Down-Regulation in Patients with Colorectal Cancer
por: Kang, Pil Sung, et al.
Publicado: (2012)

Pharmacologic Blockade of 15-PGDH Protects Against Acute Renal Injury Induced by LPS in Mice
por: Miao, Shuying, et al.
Publicado: (2020)

Early pregnancy loss in 15-hydroxyprostaglandin dehydrogenase knockout (15-HPGD(−/−)) mice due to requirement for embryo 15-HPGD activity
por: Roizen, Jeffrey D., et al.
Publicado: (2019)

15-Hydroxyprostaglandin dehydrogenase is upregulated by hydroxychloroquine in rheumatoid arthritis fibroblast-like synoviocytes
por: KIM, HAK-JAE, et al.
Publicado: (2015)

Sex Differential in 15‐Hydroxyprostaglandin Dehydrogenase Levels in the Lumen of Human Intracranial Aneurysms
por: Chalouhi, Nohra, et al.
Publicado: (2017)

In-vitro Wound Healing Effect of 15-Hydroxyprostaglandin Dehydrogenase Inhibitor from Plant
por: Karna, Sandeep
Publicado: (2017)

miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer
por: Monteleone, Nicholas J., et al.
Publicado: (2019)

15-Hydroxyprostaglandin Dehydrogenase in Colorectal Mucosa as a Potential Biomarker for Predicting Colorectal Neoplasms
por: Lee, Hyo Jeong, et al.
Publicado: (2013)

miR-620 promotes tumor radioresistance by targeting 15-hydroxyprostaglandin dehydrogenase (HPGD)
por: Huang, Xiaoyong, et al.
Publicado: (2015)

Therapeutic targeting of 15-PGDH in murine pulmonary fibrosis
por: Smith, Julianne N. P., et al.
Publicado: (2020)

Treatment of acromegaly by rosiglitazone via upregulating 15-PGDH in both pituitary adenoma and liver
por: Zhang, Yichao, et al.
Publicado: (2021)

11-Oxoeicosatetraenoic Acid Is a Cyclooxygenase-2/15-Hydroxyprostaglandin Dehydrogenase-Derived Antiproliferative Eicosanoid
por: Liu, Xiaojing, et al.
Publicado: (2011)

Effect of 15-hydroxyprostaglandin dehydrogenase gene on the proliferation of gastric cancer cell murine forestomach carcinoma
por: LI, LIHUA, et al.
Publicado: (2014)

MicroRNA-21 induces loss of 15-hydroxyprostaglandin dehydrogenase in early gastric tubular adenocarcinoma
por: Park, Young Soo, et al.
Publicado: (2018)

15-PGDH regulates hematopoietic and gastrointestinal fitness during aging
por: Ho, Won Jin, et al.
Publicado: (2022)

15-Hydroxyprostaglandin dehydrogenase as a marker in colon carcinogenesis: analysis of the prostaglandin pathway in human colonic tissue
por: Yang, Dong-Hoon, et al.
Publicado: (2017)

Tumour suppressor 15-hydroxyprostaglandin dehydrogenase induces differentiation in colon cancer via GLI1 inhibition
por: Satapathy, Shakti Ranjan, et al.
Publicado: (2020)

Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies
por: St John, M A, et al.
Publicado: (2012)

15-PGDH inhibition activates the splenic niche to promote hematopoietic regeneration
por: Smith, Julianne N.P., et al.
Publicado: (2021)

Polymer Microparticles Prolong Delivery of the 15-PGDH Inhibitor SW033291
por: Dogan, Alan B., et al.
Publicado: (2021)

High-Affinity Inhibitors of Human NAD(+)-Dependent 15-Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships
por: Niesen, Frank H., et al.
Publicado: (2010)

Expression of 15-hydroxyprostaglandin dehydrogenase and cyclooxygenase-2 in non-small cell lung cancer: Correlations with angiogenesis and prognosis
por: LI, YING, et al.
Publicado: (2014)

Rebamipide, a mucoprotective drug, inhibits NSAIDs-induced gastric mucosal injury: possible involvement of the downregulation of 15-hydroxyprostaglandin dehydrogenase
por: Tanigawa, Tetsuya, et al.
Publicado: (2011)

Downregulation of 15‐hydroxyprostaglandin dehydrogenase by interleukin‐1β from activated macrophages leads to poor prognosis in pancreatic cancer
por: Arima, Kota, et al.
Publicado: (2018)

Compound Heterozygous Pathogenic Variants of the 15-Hydroxyprostaglandin Dehydrogenase Gene in a Patient With Hypertrophic Osteoarthropathy: First Case in Korea
por: Ryu, Mi Ra, et al.
Publicado: (2019)

15-PGDH Expression in Gastric Cancer: A Potential Role in Anti-Tumor Immunity
por: Li, Yaling, et al.
Publicado: (2020)

Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERα-positive breast cancer
por: Volpato, Milene, et al.
Publicado: (2020)

Association of 15-hydroxyprostaglandin dehydrogenate and poor prognosis of obese breast cancer patients
por: Wu, Ruxing, et al.
Publicado: (2017)

Downregulation of 15-PGDH enhances MASH-HCC development via fatty acid-induced T-cell exhaustion
por: Hu, Xichen, et al.
Publicado: (2023)

Tumor microenvironmental 15‐PGDH depletion promotes fibrotic tumor formation and angiogenesis in pancreatic cancer
por: Bu, Luke, et al.
Publicado: (2022)

Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system
por: Huang, Wei, et al.
Publicado: (2023)

MicroRNA-21 regulates prostaglandin E2 signaling pathway by targeting 15-hydroxyprostaglandin dehydrogenase in tongue squamous cell carcinoma
por: He, Qianting, et al.
Publicado: (2016)

A potential anti-tumor effect of leukotriene C(4) through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells
por: Mehdawi, Lubna M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_kbltu3b3gltt4oqd0e65pun2tu