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Computation and measurement of cell decision making errors using single cell data

In this study a new computational method is developed to quantify decision making errors in cells, caused by noise and signaling failures. Analysis of tumor necrosis factor (TNF) signaling pathway which regulates the transcription factor Nuclear Factor κB (NF-κB) using this method identifies two typ...

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Detalles Bibliográficos
Autores principales: Habibi, Iman, Cheong, Raymond, Lipniacki, Tomasz, Levchenko, Andre, Emamian, Effat S., Abdi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397092/
https://www.ncbi.nlm.nih.gov/pubmed/28379950
http://dx.doi.org/10.1371/journal.pcbi.1005436