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The paradoxical functions of EGFR during breast cancer progression

The epidermal growth factor receptor (EGFR) is one of the most well-studied signaling pathways in cancer progression. As a result, numerous therapeutics including small-molecule inhibitors and monoclonal antibodies have been developed to target this critical oncogenic driver. Several of these EGFR i...

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Detalles Bibliográficos
Autores principales: Ali, Remah, Wendt, Michael K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397119/
https://www.ncbi.nlm.nih.gov/pubmed/28435746
http://dx.doi.org/10.1038/sigtrans.2016.42