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A murine preclinical syngeneic transplantation model for breast cancer precision medicine

We previously demonstrated that altered activity of lysophosphatidic acid in murine mammary glands promotes tumorigenesis. We have now established and characterized a heterogeneous collection of mouse-derived syngeneic transplants (MDSTs) as preclinical platforms for the assessment of personalized p...

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Detalles Bibliográficos
Autores principales: Federico, Lorenzo, Chong, Zechen, Zhang, Dong, McGrail, Daniel J., Zhao, Wei, Jeong, Kang Jin, Vellano, Christopher P., Ju, Zhenlin, Gagea, Mihai, Liu, Shuying, Mitra, Shreya, Dennison, Jennifer B., Lorenzi, Philip L., Cardnell, Robert, Diao, Lixia, Wang, Jing, Lu, Yiling, Byers, Lauren A., Perou, Charles M., Lin, Shiaw-Yih, Mills, Gordon B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397135/
https://www.ncbi.nlm.nih.gov/pubmed/28439535
http://dx.doi.org/10.1126/sciadv.1600957