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The RNA-binding protein Secisbp2 differentially modulates UGA codon reassignment and RNA decay

Dual-assignment of codons as termination and elongation codons is used to expand the genetic code. In mammals, UGA can be reassigned to selenocysteine during translation of selenoproteins by a mechanism involving a 3΄ untranslated region (UTR) selenocysteine insertion sequence (SECIS) and the SECIS-...

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Detalles Bibliográficos
Autores principales: Fradejas-Villar, Noelia, Seeher, Sandra, Anderson, Christine B., Doengi, Michael, Carlson, Bradley A., Hatfield, Dolph L., Schweizer, Ulrich, Howard, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397149/
https://www.ncbi.nlm.nih.gov/pubmed/27956496
http://dx.doi.org/10.1093/nar/gkw1255