Analyzing DNA curvature and its impact on the ionic environment: application to molecular dynamics simulations of minicircles

We propose a method for analyzing the magnitude and direction of curvature within nucleic acids, based on the curvilinear helical axis calculated by Curves+. The method is applied to analyzing curvature within minicircles constructed with varying degrees of over- or under-twisting. Using the molecul...

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Detalles Bibliográficos
Autores principales: Pasi, Marco, Zakrzewska, Krystyna, Maddocks, John H., Lavery, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397150/
https://www.ncbi.nlm.nih.gov/pubmed/28180333
http://dx.doi.org/10.1093/nar/gkx092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397150/
https://www.ncbi.nlm.nih.gov/pubmed/28180333
http://dx.doi.org/10.1093/nar/gkx092

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