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Chromosomal dynamics predicted by an elastic network model explains genome-wide accessibility and long-range couplings
Understanding the three-dimensional (3D) architecture of chromatin and its relation to gene expression and regulation is fundamental to understanding how the genome functions. Advances in Hi-C technology now permit us to study 3D genome organization, but we still lack an understanding of the structu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397156/ https://www.ncbi.nlm.nih.gov/pubmed/28334818 http://dx.doi.org/10.1093/nar/gkx172 |