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Chromosomal dynamics predicted by an elastic network model explains genome-wide accessibility and long-range couplings

Understanding the three-dimensional (3D) architecture of chromatin and its relation to gene expression and regulation is fundamental to understanding how the genome functions. Advances in Hi-C technology now permit us to study 3D genome organization, but we still lack an understanding of the structu...

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Detalles Bibliográficos
Autores principales: Sauerwald, Natalie, Zhang, She, Kingsford, Carl, Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397156/
https://www.ncbi.nlm.nih.gov/pubmed/28334818
http://dx.doi.org/10.1093/nar/gkx172