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The 5΄ UTR of the type I toxin ZorO can both inhibit and enhance translation

Many bacterial type I toxin mRNAs possess a long 5΄ untranslated region (UTR) that serves as the target site of the corresponding antitoxin sRNA. This is the case for the zorO-orzO type I system where the OrzO antitoxin base pairs to the 174-nucleotide zorO 5΄ UTR. Here, we demonstrate that the full...

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Detalles Bibliográficos
Autores principales: Wen, Jia, Harp, John R., Fozo, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397157/
https://www.ncbi.nlm.nih.gov/pubmed/27903909
http://dx.doi.org/10.1093/nar/gkw1172