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Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5

RecQ helicases are important maintainers of genome integrity with distinct roles in almost every cellular process requiring access to DNA. RECQL5 is one of five human RecQ proteins and is particularly versatile in this regard, forming protein complexes with a diverse set of cellular partners in orde...

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Detalles Bibliográficos
Autores principales: Newman, Joseph A., Aitkenhead, Hazel, Savitsky, Pavel, Gileadi, Opher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397160/
https://www.ncbi.nlm.nih.gov/pubmed/28100692
http://dx.doi.org/10.1093/nar/gkw1362