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Succession of splicing regulatory elements determines cryptic 5΄ss functionality

A critical step in exon definition is the recognition of a proper splice donor (5΄ss) by the 5’ end of U1 snRNA. In the selection of appropriate 5΄ss, cis-acting splicing regulatory elements (SREs) are indispensable. As a model for 5΄ss recognition, we investigated cryptic 5΄ss selection within the...

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Detalles Bibliográficos
Autores principales: Brillen, Anna-Lena, Schöneweis, Katrin, Walotka, Lara, Hartmann, Linda, Müller, Lisa, Ptok, Johannes, Kaisers, Wolfgang, Poschmann, Gereon, Stühler, Kai, Buratti, Emanuele, Theiss, Stephan, Schaal, Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397162/
https://www.ncbi.nlm.nih.gov/pubmed/28039323
http://dx.doi.org/10.1093/nar/gkw1317